MetaCyc Pathway: ketolysis in Herbaspirillum seropedicae SmR1

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Reactions and Genes Carbon source Phenylacetic 5 mM
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3-hydroxybutyrate dehydrogenase:
(R)-3-hydroxybutanoate + NAD+→acetoacetate + NADH + H+ (EC 1.1.1.30)
HSERO_RS06265 -0.0
HSERO_RS17235 +0.1
HSERO_RS21160 +0.1
3-oxoacid CoA-transferase:
acetoacetate + succinyl-CoA→acetoacetyl-CoA + succinate (EC 2.8.3.5)
HSERO_RS23185 -2.8
HSERO_RS23190 N.D.
Acetyl-CoA C-acyltransferase (in reverse):
acetoacetyl-CoA + coenzyme A→2 acetyl-CoA (EC 2.3.1.16; 2.3.1.9)
HSERO_RS01180 -0.3
HSERO_RS01265 -0.4
HSERO_RS04635 +0.4
HSERO_RS19070 -0.2
HSERO_RS19990 +0.1
HSERO_RS20030 +0.1
HSERO_RS20660 -4.9

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information