MetaCyc Pathway: ppGpp metabolism in Klebsiella michiganensis M5al

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Reactions and Genes Thymine (N)
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Nucleoside-diphosphate kinase:
GDP + ATP→GTP + ADP (EC 2.7.4.6)
BWI76_RS06840 N.D.
BWI76_RS21100 -0.9
GTP diphosphokinase:
GTP + ATP→pppGpp + AMP + H+ (EC 2.7.6.5)
BWI76_RS22805 -5.1
BWI76_RS27430 -3.0
Guanosine-5'-triphosphate,3'-diphosphate diphosphatase:
pppGpp + H2O→ppGpp + H+ + phosphate (EC 3.6.1.40)
BWI76_RS01060 -2.3
BWI76_RS04510 -0.5
BWI76_RS21000 -1.3
Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase:
pppGpp + H2O→GTP + diphosphate (EC 3.1.7.2)
BWI76_RS27430 -3.0
Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase:
ppGpp + H2O→GDP + diphosphate (EC 3.1.7.2)
BWI76_RS27430 -3.0
GTP diphosphokinase:
GDP + ATP→ppGpp + AMP + H+ (EC 2.7.6.5)
BWI76_RS22805 -5.1
BWI76_RS27430 -3.0

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information