MetaCyc Pathway: urate conversion to allantoin II in Klebsiella michiganensis M5al

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Reactions and Genes Inosine (N)
remove
urate + NADH + dioxygen + H+→(S)-5-hydroxyisourate + NAD+ + H2O (EC 1.14.13.113)
BWI76_RS10500 -3.6
Hydroxyisourate hydrolase:
(S)-5-hydroxyisourate + H2O→(S)-2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline + H+ (EC 3.5.2.17)
BWI76_RS10515 N.D.
BWI76_RS17590 +0.1
(S)-2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline + H+→(S)-(+)-allantoin + CO2 (EC 4.1.1.97)
BWI76_RS10510 -5.2

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information