MetaCyc Pathway: superpathway of purines degradation in plants in Klebsiella michiganensis M5al

Add experiment(s):


Reactions and Genes Inosine (N)
remove
Adenosine-phosphate deaminase:
AMP + H+ + H2O→IMP + ammonium (EC 3.5.4.17; 3.5.4.6)
No genes
5'-nucleotidase:
GMP + H2O→guanosine + phosphate (EC 3.1.3.5)
BWI76_RS01930 +0.3
BWI76_RS03465 +0.1
BWI76_RS04095 +0.1
BWI76_RS06865 +0.0
BWI76_RS20210 +0.2
BWI76_RS22660 +0.2
BWI76_RS26140 +0.4
Guanosine deaminase:
guanosine + H+ + H2O→xanthosine + ammonium (EC 3.5.4.15)
No genes
IMP dehydrogenase:
IMP + NAD+ + H2O→XMP + NADH + H+ (EC 1.1.1.205)
BWI76_RS21030 N.D.
5'-nucleotidase:
IMP + H2O→inosine + phosphate (EC 3.1.3.5; 3.1.3.99)
BWI76_RS01930 +0.3
BWI76_RS03465 +0.1
BWI76_RS04095 +0.1
BWI76_RS06160 +0.1
BWI76_RS06865 +0.0
BWI76_RS20210 +0.2
BWI76_RS22660 +0.2
BWI76_RS26140 +0.4
Purine nucleosidase:
guanosine + H2O→guanine + D-ribofuranose (EC 3.2.2.1)
BWI76_RS04360 -0.3
BWI76_RS13490 -0.1
Guanine deaminase:
guanine + H+ + H2O→xanthine + ammonium (EC 3.5.4.3)
BWI76_RS10520 -0.1
Inosine nucleosidase:
inosine + H2O→hypoxanthine + D-ribofuranose (EC 3.2.2.2)
BWI76_RS04360 -0.3
BWI76_RS13490 -0.1
5'-nucleotidase:
XMP + H2O→xanthosine + phosphate (EC 3.1.3.5)
BWI76_RS01930 +0.3
BWI76_RS03465 +0.1
BWI76_RS04095 +0.1
BWI76_RS06865 +0.0
BWI76_RS20210 +0.2
BWI76_RS22660 +0.2
Xanthine dehydrogenase:
hypoxanthine + NAD+ + H2O→xanthine + NADH + H+ (EC 1.17.1.4)
BWI76_RS17570 -0.6
BWI76_RS17575 +0.1
Purine nucleosidase:
xanthosine + H2O→xanthine + D-ribofuranose (EC 3.2.2.1)
BWI76_RS04360 -0.3
BWI76_RS13490 -0.1
Xanthine dehydrogenase:
xanthine + NAD+ + H2O→urate + NADH + H+ (EC 1.17.1.4)
BWI76_RS17570 -0.6
BWI76_RS17575 +0.1
Urate oxidase:
urate + dioxygen + H2O→(S)-5-hydroxyisourate + hydrogen peroxide (EC 1.7.3.3)
BWI76_RS10540 -5.9
Hydroxyisourate hydrolase:
(S)-5-hydroxyisourate + H2O→(S)-2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline + H+ (EC 3.5.2.17)
BWI76_RS10515 N.D.
BWI76_RS17590 +0.1
(S)-2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline + H+→(S)-(+)-allantoin + CO2 (EC 4.1.1.97)
BWI76_RS10510 -5.2
Allantoinase:
(S)-(+)-allantoin + H2O→allantoate + H+ (EC 3.5.2.5)
BWI76_RS07015 -0.1
Allantoicase:
allantoate + H2O→(S)-ureidoglycolate + urea (EC 3.5.3.4)
No genes
Ureidoglycolate lyase:
(S)-ureidoglycolate→glyoxylate + urea (EC 4.3.2.3)
BWI76_RS06980 -0.2

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information