MetaCyc Pathway: L-tyrosine degradation I in Klebsiella michiganensis M5al

Add experiment(s):


Reactions and Genes L-Tryptophan (N)
remove
Aspartate transaminase:
L-tyrosine + 2-oxoglutarate→3-(4-hydroxyphenyl)pyruvate + L-glutamate (EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
BWI76_RS01925 -4.3
BWI76_RS03690 +0.0
BWI76_RS06660 +0.1
BWI76_RS06750 -0.0
BWI76_RS07560 +0.0
BWI76_RS07570 +0.2
BWI76_RS08675 -0.3
BWI76_RS09870 -1.1
BWI76_RS10245 +0.3
BWI76_RS12985 -0.5
BWI76_RS13400 +0.2
BWI76_RS18930 -4.0
BWI76_RS20205 -1.1
BWI76_RS22035 -0.0
BWI76_RS24235 -0.4
4-hydroxyphenylpyruvate dioxygenase:
3-(4-hydroxyphenyl)pyruvate + dioxygen→homogentisate + CO2 (EC 1.13.11.27)
BWI76_RS04635 -0.1
BWI76_RS16940 -0.0
BWI76_RS16945 -0.1
Homogentisate 1,2-dioxygenase:
homogentisate + dioxygen→4-maleyl-acetoacetate + H+ (EC 1.13.11.5)
No genes
Maleylacetoacetate isomerase:
4-maleyl-acetoacetate→4-fumaryl-acetoacetate (EC 5.2.1.2)
BWI76_RS19575 -0.1
Fumarylacetoacetase:
4-fumaryl-acetoacetate + H2O→acetoacetate + fumarate + H+ (EC 3.7.1.2)
BWI76_RS19580 +0.4

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information