MetaCyc Pathway: L-phenylalanine degradation VI (reductive Stickland reaction) in Klebsiella michiganensis M5al

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Reactions and Genes L-Tryptophan (N)
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Aspartate transaminase:
L-phenylalanine + 2-oxoglutarate→3-phenyl-2-oxopropanoate + L-glutamate (EC 2.6.1.1; 2.6.1.27; 2.6.1.57)
BWI76_RS00970 -0.5
BWI76_RS01925 -4.3
BWI76_RS03690 +0.0
BWI76_RS06660 +0.1
BWI76_RS06750 -0.0
BWI76_RS07560 +0.0
BWI76_RS07570 +0.2
BWI76_RS08675 -0.3
BWI76_RS09870 -1.1
BWI76_RS10245 +0.3
BWI76_RS12985 -0.5
BWI76_RS13400 +0.2
BWI76_RS18930 -4.0
BWI76_RS20205 -1.1
BWI76_RS22035 -0.0
BWI76_RS24235 -0.4
Indolelactate dehydrogenase (in reverse):
3-phenyl-2-oxopropanoate + NADH + H+→(R)-3-(phenyl)lactate + NAD+ (EC 1.1.1.110)
No genes
Cinnamoyl-CoA:phenyllactate CoA-transferase:
(R)-3-(phenyl)lactate + (E)-cinnamoyl-CoA→(R)-3-(phenyl)lactoyl-CoA + trans-cinnamate (EC 2.8.3.17)
No genes
trans-cinnamate + a reduced electron-transfer flavoprotein→3-phenylpropanoate + an oxidized electron-transfer flavoprotein + H+ (EC 1.3.8.15)
No genes
(R)-3-(phenyl)lactoyl-CoA→(E)-cinnamoyl-CoA + H2O (EC 4.2.1.175)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information