MetaCyc Pathway: L-tyrosine degradation III in Klebsiella michiganensis M5al

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Reactions and Genes L-Phenylalanine (N)
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Phenylalanine(histidine) transaminase:
L-tyrosine + pyruvate→3-(4-hydroxyphenyl)pyruvate + L-alanine (EC 2.6.1.58)
No genes
Aspartate transaminase:
L-tyrosine + 2-oxoglutarate→3-(4-hydroxyphenyl)pyruvate + L-glutamate (EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
BWI76_RS01925 -2.5
BWI76_RS03690 -0.2
BWI76_RS06660 -0.2
BWI76_RS06750 +0.1
BWI76_RS07560 -0.1
BWI76_RS07570 +0.1
BWI76_RS08675 +0.2
BWI76_RS09870 -2.3
BWI76_RS10245 -0.2
BWI76_RS12985 +0.1
BWI76_RS13400 +0.2
BWI76_RS18930 -5.2
BWI76_RS20205 -0.9
BWI76_RS22035 +0.0
BWI76_RS24235 -0.2
4-hydroxyphenylpyruvate decarboxylase:
3-(4-hydroxyphenyl)pyruvate + H+→(4-hydroxyphenyl)acetaldehyde + CO2 (EC 4.1.1.80)
No genes
Alcohol dehydrogenase (in reverse):
(4-hydroxyphenyl)acetaldehyde + NADH + H+→4-tyrosol + NAD+ (EC 1.1.1.1)
BWI76_RS00645 +0.3
BWI76_RS02835 -0.0
BWI76_RS03140 -0.1
BWI76_RS03320 +0.1
BWI76_RS12395 -0.3
BWI76_RS13800 +0.3
BWI76_RS15240 +0.1
BWI76_RS17250 -0.2
BWI76_RS25510 +0.2
BWI76_RS27960 -0.5

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information