MetaCyc Pathway: TCA cycle VIII (Chlamydia) in Klebsiella michiganensis M5al

Reactions and Genes	L-Leucine (N)
2-oxoglutarate + coenzyme A + NAD+→succinyl-CoA + CO2 + NADH (EC 1.2.1.105)
BWI76_RS04890	N.D.
Succinate--CoA ligase (ADP-forming) (in reverse): succinyl-CoA + ADP + phosphate→succinate + ATP + coenzyme A (EC 6.2.1.5)
BWI76_RS08425	+0.3
BWI76_RS08430	+0.1
Succinate dehydrogenase (ubiquinone): succinate[in] + an electron-transfer quinone→fumarate[in] + an electron-transfer quinol (EC 1.3.5.1)
No genes
Fumarate hydratase (in reverse): fumarate + H2O→(S)-malate (EC 4.2.1.2)
BWI76_RS08450	+0.2
BWI76_RS16115	+0.3
BWI76_RS16270	-0.1
BWI76_RS16275	+0.8
BWI76_RS16955	-0.9
Malate dehydrogenase: (S)-malate + NAD+→oxaloacetate + NADH + H+ (EC 1.1.1.37; 1.1.1.38)
BWI76_RS13830	+0.1
BWI76_RS16775	+0.4
BWI76_RS25420	+0.2
Aspartate transaminase (in reverse): oxaloacetate + L-glutamate→2-oxoglutarate + L-aspartate (EC 2.6.1.1)
BWI76_RS03690	-0.1
BWI76_RS06660	+0.0
BWI76_RS06750	+0.1
BWI76_RS07560	+0.1
BWI76_RS07570	+0.1
BWI76_RS08675	+0.1
BWI76_RS09870	-0.1
BWI76_RS10245	+0.2
BWI76_RS12985	-0.1
BWI76_RS13400	+0.4
BWI76_RS20205	-0.6
BWI76_RS22035	+0.2
BWI76_RS24235	-1.6

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information