MetaCyc Pathway: L-tyrosine degradation V (reductive Stickland reaction) in Klebsiella michiganensis M5al

Reactions and Genes	L-Leucine (N)
Aspartate transaminase: L-tyrosine + 2-oxoglutarate→3-(4-hydroxyphenyl)pyruvate + L-glutamate (EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
BWI76_RS01925	-0.6
BWI76_RS03690	-0.1
BWI76_RS06660	+0.0
BWI76_RS06750	+0.1
BWI76_RS07560	+0.1
BWI76_RS07570	+0.1
BWI76_RS08675	+0.1
BWI76_RS09870	-0.1
BWI76_RS10245	+0.2
BWI76_RS12985	-0.1
BWI76_RS13400	+0.4
BWI76_RS18930	-6.3
BWI76_RS20205	-0.6
BWI76_RS22035	+0.2
BWI76_RS24235	-1.6
Indolelactate dehydrogenase (in reverse): 3-(4-hydroxyphenyl)pyruvate + NADH + H+→(R)-3-(4-hydroxyphenyl)lactate + NAD+ (EC 1.1.1.110)
No genes
Cinnamoyl-CoA:phenyllactate CoA-transferase: (R)-3-(4-hydroxyphenyl)lactate + (E)-4-coumaroyl-CoA→4-coumarate + (R)-3-(4-hydroxyphenyl)lactoyl-CoA (EC 2.8.3.17)
No genes
4-coumarate + a reduced electron-transfer flavoprotein→phloretate + an oxidized electron-transfer flavoprotein + H+ (EC 1.3.8.15)
No genes
(R)-3-(4-hydroxyphenyl)lactoyl-CoA→(E)-4-coumaroyl-CoA + H2O (EC 4.2.1.175)
No genes

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information