MetaCyc Pathway: L-isoleucine degradation II in Klebsiella michiganensis M5al

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Reactions and Genes L-Leucine (N)
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Branched-chain-amino-acid transaminase:
L-isoleucine + 2-oxoglutarate→(3S)-3-methyl-2-oxopentanoate + L-glutamate (EC 2.6.1.42)
BWI76_RS00970 -1.4
BWI76_RS10365 +0.5
BWI76_RS24235 -1.6
Branched-chain-2-oxoacid decarboxylase:
(3S)-3-methyl-2-oxopentanoate + H+→2-methylbutanal + CO2 (EC 4.1.1.72)
No genes
Alcohol dehydrogenase (in reverse):
2-methylbutanal + NADH + H+→2-methylbutanol + NAD+ (EC 1.1.1.1)
BWI76_RS00645 +0.0
BWI76_RS02835 -0.1
BWI76_RS03140 -0.0
BWI76_RS03320 +0.1
BWI76_RS12395 -0.4
BWI76_RS13800 -0.1
BWI76_RS15240 +0.0
BWI76_RS17250 +0.1
BWI76_RS25510 +0.3
BWI76_RS27960 -0.1

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information