MetaCyc Pathway: superpathway of fatty acid biosynthesis initiation in Pseudomonas fluorescens FW300-N2E2

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Reactions and Genes tungstate 0.05 M
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[Acyl-carrier-protein] S-acetyltransferase:
acetyl-CoA + a soluble [acyl-carrier protein]→an acetyl-[acp] + coenzyme A (EC 2.3.1.38)
No genes
acetyl-CoA + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine→malonyl-CoA + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine (EC 2.1.3.15)
Pf6N2E2_3053 N.D.
Pf6N2E2_72 N.D.
[Acyl-carrier-protein] S-malonyltransferase:
malonyl-CoA + a soluble [acyl-carrier protein]→a malonyl-[acp] + coenzyme A (EC 2.3.1.39)
Pf6N2E2_4625 +0.1
Pf6N2E2_5951 N.D.
Pf6N2E2_6 +1.1
Beta-ketoacyl-acyl-carrier-protein synthase III:
acetyl-CoA + a malonyl-[acp] + H+→an acetoacetyl-[acp] + CO2 + coenzyme A (EC 2.3.1.180)
Pf6N2E2_2605 +0.9
Pf6N2E2_2693 +0.6
Beta-ketoacyl-acyl-carrier-protein synthase II:
an acetyl-[acp] + a malonyl-[acp] + H+→an acetoacetyl-[acp] + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.179; 2.3.1.41)
Pf6N2E2_1178 +0.6
Pf6N2E2_3726 -0.2
Pf6N2E2_3729 -0.4
Pf6N2E2_5870 N.D.
Pf6N2E2_5954 N.D.
Pf6N2E2_835 +0.2

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information