| Reactions and Genes | m.b. Fusidic 0.0002 mg/ml |
|---|
| remove |
| (5Z,8Z,11Z,14Z,17Z)-icosapentaenoyl-CoA + malonyl-CoA + H+→(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA + CO2 + coenzyme A |
| No genes |
| (5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA + NAD(P)H + H+→(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA + NAD(P)+ (EC 1.1.1.330) |
| No genes |
| (3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA→(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + H2O (EC 4.2.1.134) |
| No genes |
| (2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + a reduced two electron carrier→(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA + an oxidized electron carrier (EC 1.3.1.93) |
| No genes |
| (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA + malonyl-CoA + H+→(9Z,12Z,15Z,18Z,21Z)-3-oxotetracosapentaenoyl-CoA + CO2 + coenzyme A |
| No genes |
| (9Z,12Z,15Z,18Z,21Z)-3-oxotetracosapentaenoyl-CoA + NADPH + H+→(3R,9Z,12Z,15Z,18Z,21Z)-3-hydroxytetracosapentaenoyl-CoA + NADP+ (EC 1.1.1.330) |
| No genes |
| (3R,9Z,12Z,15Z,18Z,21Z)-3-hydroxytetracosapentaenoyl-CoA→(2E,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + H2O (EC 4.2.1.134) |
| No genes |
| (2E,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + NADPH + H+→(9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA + NADP+ (EC 1.3.1.93) |
| No genes |
Linoleoyl-CoA desaturase:
(9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA + 2 a ferrocytochrome b5 + dioxygen + 2 H+→(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + 2 a ferricytochrome b5 + 2 H2O (EC 1.14.19.3) |
| No genes |
Acyl-CoA oxidase:
(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + dioxygen→(2E,6Z,9Z,12Z,15Z,18Z,21Z)-tetracosaheptaenoyl-CoA + hydrogen peroxide (EC 1.3.3.6) |
| No genes |
Enoyl-CoA hydratase (in reverse):
(2E,6Z,9Z,12Z,15Z,18Z,21Z)-tetracosaheptaenoyl-CoA + H2O→(3S,6Z,9Z,12Z,15Z,18Z,21Z)-3-hydroxytetracosahexaenoyl-CoA (EC 4.2.1.17) |
| PGA1_c12020 | +0.5 |
| PGA1_c14440 | -0.0 |
| PGA1_c15660 | +0.0 |
| PGA1_c16990 | -3.2 |
| PGA1_c17350 | +1.6 |
| PGA1_c22740 | +0.0 |
| PGA1_c23460 | -0.1 |
| PGA1_c23920 | -0.1 |
| PGA1_c26820 | -0.2 |
| PGA1_c33450 | -0.2 |
| PGA1_c34200 | -0.0 |
| PGA1_c36500 | N.D. |
| PGA1_262p01540 | +0.1 |
| PGA1_262p01850 | +0.1 |
| PGA1_262p01980 | -0.1 |
| PGA1_c04110 | +0.5 |
| (3S,6Z,9Z,12Z,15Z,18Z,21Z)-3-hydroxytetracosahexaenoyl-CoA + NAD+→(6Z,9Z,12Z,15Z,18Z,21Z)-3-oxotetracosahexaenoyl-CoA + NADH + H+ |
| No genes |
Acetyl-CoA C-acyltransferase (in reverse):
(6Z,9Z,12Z,15Z,18Z,21Z)-3-oxotetracosahexaenoyl-CoA + coenzyme A→(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + acetyl-CoA (EC 2.3.1.16) |
| PGA1_c12030 | +0.5 |
| PGA1_c22730 | +0.0 |
| PGA1_c33180 | +0.0 |
| PGA1_c03400 | +0.1 |
| PGA1_c34350 | +0.3 |
| PGA1_c04090 | +0.1 |
| PGA1_c04120 | +0.0 |
| (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + a glycerolipid→a [glycerolipid]-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + coenzyme A |
| No genes |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information