MetaCyc Pathway: L-ornithine biosynthesis I in Klebsiella michiganensis M5al

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Reactions and Genes L-Histidine (N)
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Amino-acid N-acetyltransferase:
L-glutamate + acetyl-CoA→N-acetyl-L-glutamate + coenzyme A + H+ (EC 2.3.1.1)
BWI76_RS23220 -5.7
Acetylglutamate kinase:
N-acetyl-L-glutamate + ATP→N-acetylglutamyl-phosphate + ADP (EC 2.7.2.8)
BWI76_RS00850 -8.1
N-acetyl-gamma-glutamyl-phosphate reductase (in reverse):
N-acetylglutamyl-phosphate + NADPH + H+→N-acetyl-L-glutamate 5-semialdehyde + NADP+ + phosphate (EC 1.2.1.38)
BWI76_RS00845 -5.1
Acetylornithine transaminase (in reverse):
N-acetyl-L-glutamate 5-semialdehyde + L-glutamate→N-acetyl-L-ornithine + 2-oxoglutarate (EC 2.6.1.11)
BWI76_RS11670 -0.1
BWI76_RS26000 -0.4
Acetylornithine deacetylase:
N-acetyl-L-ornithine + H2O→L-ornithine + acetate (EC 3.5.1.16)
BWI76_RS00840 -2.7
BWI76_RS10270 +0.2
BWI76_RS12865 -0.1
BWI76_RS14620 -0.1

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information