MetaCyc Pathway: L-arginine biosynthesis III (via N-acetyl-L-citrulline) in Paraburkholderia bryophila 376MFSha3.1

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Reactions and Genes 4-Hydroxybenzoic Acid (C)
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Carbamoyl-phosphate synthase (glutamine-hydrolyzing):
hydrogen carbonate + 2 ATP + L-glutamine + H2O→carbamoyl phosphate + L-glutamate + 2 ADP + 2 H+ + phosphate (EC 6.3.5.5)
H281DRAFT_04402 N.D.
H281DRAFT_04403 N.D.
Amino-acid N-acetyltransferase:
L-glutamate + acetyl-CoA→N-acetyl-L-glutamate + coenzyme A + H+ (EC 2.3.1.1)
H281DRAFT_00444 -0.8
H281DRAFT_06249 -0.3
Acetylglutamate kinase:
N-acetyl-L-glutamate + ATP→N-acetylglutamyl-phosphate + ADP (EC 2.7.2.8)
H281DRAFT_02211 N.D.
N-acetyl-gamma-glutamyl-phosphate reductase (in reverse):
N-acetylglutamyl-phosphate + NADPH + H+→N-acetyl-L-glutamate 5-semialdehyde + NADP+ + phosphate (EC 1.2.1.38)
H281DRAFT_02654 +0.2
H281DRAFT_05840 -0.9
Acetylornithine transaminase (in reverse):
N-acetyl-L-glutamate 5-semialdehyde + L-glutamate→N-acetyl-L-ornithine + 2-oxoglutarate (EC 2.6.1.11)
H281DRAFT_04057 -1.3
H281DRAFT_06478 +0.3
N-acetylornithine carbamoyltransferase:
carbamoyl phosphate + N-acetyl-L-ornithine→N-acetyl-L-citrulline + H+ + phosphate (EC 2.1.3.9)
No genes
Acetylornithine deacetylase:
N-acetyl-L-citrulline + H2O→L-citrulline + acetate (EC 3.5.1.16)
H281DRAFT_00879 +0.5
H281DRAFT_04940 +0.4
Argininosuccinate synthase:
L-citrulline + ATP + L-aspartate→L-arginino-succinate + AMP + diphosphate + H+ (EC 6.3.4.5)
H281DRAFT_04120 -6.8
Argininosuccinate lyase:
L-arginino-succinate→L-arginine + fumarate (EC 4.3.2.1)
H281DRAFT_00194 -3.6

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information