MetaCyc Pathway: GABA shunt I in Klebsiella michiganensis M5al

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Reactions and Genes Putrescine (N)
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Glutamate dehydrogenase (NAD(P)(+)) (in reverse):
2-oxoglutarate + ammonium + NAD(P)H + H+→L-glutamate + NAD(P)+ + H2O (EC 1.4.1.3)
BWI76_RS13195 -0.0
Glutamate decarboxylase:
L-glutamate + H+→4-aminobutanoate + CO2 (EC 4.1.1.15)
No genes
4-aminobutyrate transaminase:
2-oxoglutarate + 4-aminobutanoate→L-glutamate + succinate semialdehyde (EC 2.6.1.19)
BWI76_RS26375 -0.7
Succinate-semialdehyde dehydrogenase:
succinate semialdehyde + NAD+ + H2O→succinate + NADH + 2 H+ (EC 1.2.1.24)
BWI76_RS03795 +0.2
BWI76_RS10695 -2.6
BWI76_RS15205 -0.5

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information