MetaCyc Pathway: L-tyrosine biosynthesis I in Klebsiella michiganensis M5al

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Reactions and Genes L-Tryptophan (N)
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Chorismate mutase:
chorismate→prephenate
(EC 5.4.99.5)
BWI76_RS21465 -3.7
BWI76_RS21475 -1.9
Prephenate dehydrogenase:
prephenate + NAD+→3-(4-hydroxyphenyl)pyruvate + CO2 + NADH
(EC 1.3.1.12)
BWI76_RS21475 -1.9
Aspartate transaminase (in reverse):
3-(4-hydroxyphenyl)pyruvate + L-glutamate→L-tyrosine + 2-oxoglutarate
(EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
BWI76_RS01925 -3.4
BWI76_RS03690 +0.1
BWI76_RS06660 +0.1
BWI76_RS06750 +0.2
BWI76_RS07560 +0.0
BWI76_RS07570 +0.3
BWI76_RS08675 -0.1
BWI76_RS09870 -0.7
BWI76_RS10245 -0.0
BWI76_RS12985 +0.1
BWI76_RS13400 -0.3
BWI76_RS18930 -5.0
BWI76_RS20205 -0.3
BWI76_RS22035 +0.0
BWI76_RS24235 +0.0

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information