MetaCyc Pathway: superpathway of Clostridium acetobutylicum solventogenic fermentation in Paraburkholderia bryophila 376MFSha3.1

Reactions and Genes	Phenylacetic (C)
Pyruvate synthase: pyruvate + coenzyme A + 2 an oxidized ferredoxin [iron-sulfur] cluster→acetyl-CoA + CO2 + H+ + 2 a reduced ferredoxin [iron-sulfur] cluster (EC 1.2.7.1)
No genes
Acetaldehyde dehydrogenase (acetylating) (in reverse): acetyl-CoA + NADH + H+→acetaldehyde + coenzyme A + NAD+ (EC 1.2.1.10)
H281DRAFT_01665	-0.1
Acetyl-CoA C-acyltransferase: 2 acetyl-CoA→acetoacetyl-CoA + coenzyme A (EC 2.3.1.16; 2.3.1.9)
H281DRAFT_00852	-1.6
H281DRAFT_00857	-0.1
H281DRAFT_00917	+0.3
H281DRAFT_01504	+0.1
H281DRAFT_02089	-0.1
H281DRAFT_04626	-0.2
H281DRAFT_05130	N.D.
H281DRAFT_05518	-0.1
H281DRAFT_05559	+0.0
H281DRAFT_05723	-5.2
H281DRAFT_06132	+0.1
Butyrate--acetoacetate CoA-transferase (in reverse): acetoacetyl-CoA + butanoate→acetoacetate + butanoyl-CoA (EC 2.8.3.9)
No genes
Butyrate--acetoacetate CoA-transferase (in reverse): acetoacetyl-CoA + acetate→acetoacetate + acetyl-CoA (EC 2.8.3.9)
H281DRAFT_02525	-0.3
Alcohol dehydrogenase (in reverse): acetaldehyde + NADH + H+→ethanol + NAD+ (EC 1.1.1.1)
H281DRAFT_01050	-0.1
H281DRAFT_01171	+0.2
H281DRAFT_01251	-0.0
H281DRAFT_02579	-0.0
H281DRAFT_02988	+0.1
H281DRAFT_03803	+0.1
H281DRAFT_04166	-0.2
H281DRAFT_05379	+0.4
H281DRAFT_05508	+0.2
3-hydroxyacyl-CoA dehydrogenase (in reverse): acetoacetyl-CoA + NADH + H+→(S)-3-hydroxybutanoyl-CoA + NAD+ (EC 1.1.1.35)
H281DRAFT_00361	-1.8
H281DRAFT_00916	-0.2
H281DRAFT_03517	-0.5
H281DRAFT_04595	-0.9
H281DRAFT_04625	-0.5
H281DRAFT_05521	+0.8
H281DRAFT_06131	-0.2
Acetoacetate decarboxylase: acetoacetate + H+→acetone + CO2 (EC 4.1.1.4)
No genes
(S)-3-hydroxybutanoyl-CoA→crotonyl-CoA + H2O (EC 4.2.1.150)
H281DRAFT_00361	-1.8
H281DRAFT_00653	+0.7
H281DRAFT_00756	-0.1
H281DRAFT_00916	-0.2
H281DRAFT_01137	N.D.
H281DRAFT_01179	-0.1
H281DRAFT_01187	+0.1
H281DRAFT_01670	+0.2
H281DRAFT_01774	N.D.
H281DRAFT_02068	-0.5
H281DRAFT_02497	-0.7
H281DRAFT_02514	-0.2
H281DRAFT_02515	N.D.
H281DRAFT_02677	+0.0
H281DRAFT_02741	+0.3
H281DRAFT_02927	+0.2
H281DRAFT_03491	N.D.
H281DRAFT_03701	+0.3
H281DRAFT_03739	+0.1
H281DRAFT_03908	-0.0
H281DRAFT_04625	-0.5
H281DRAFT_04627	-0.3
H281DRAFT_04744	-0.1
H281DRAFT_05516	+0.2
H281DRAFT_05977	-0.1
crotonyl-CoA[cytosol] + 2 NADH[cytosol] + 2 an oxidized ferredoxin [iron-sulfur] cluster[cytosol]→butanoyl-CoA[cytosol] + 2 NAD+[cytosol] + 2 a reduced ferredoxin [iron-sulfur] cluster[cytosol] (EC 1.3.1.109)
No genes
Butanal dehydrogenase (in reverse): butanoyl-CoA + NAD(P)H + H+→1-butanal + coenzyme A + NAD(P)+ (EC 1.2.1.57)
No genes
Alcohol dehydrogenase (NADP(+)) (in reverse): 1-butanal + NADPH + H+→butan-1-ol + NADP+ (EC 1.1.1.2)
H281DRAFT_04910	-0.2
1-butanal + NADH + H+→butan-1-ol + NAD+
No genes

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information