MetaCyc Pathway: 4-hydroxybenzoate biosynthesis III (plants) in Paraburkholderia bryophila 376MFSha3.1

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Reactions and Genes Phenylacetic (C)
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4-coumarate--CoA ligase:
4-coumarate + ATP + coenzyme A→(E)-4-coumaroyl-CoA + AMP + diphosphate (EC 6.2.1.12)
H281DRAFT_01278 +0.0
(E)-4-coumaroyl-CoA + H2O→3S-(4-hydroxyphenyl)-3-hydroxy-propanoyl-CoA (EC 4.1.2.61)
No genes
3-hydroxyacyl-CoA dehydrogenase:
3S-(4-hydroxyphenyl)-3-hydroxy-propanoyl-CoA + NAD+→3-(4-hydroxyphenyl)-3-oxo-propanoyl-CoA + NADH + H+ (EC 1.1.1.35)
H281DRAFT_00361 -1.8
H281DRAFT_00916 -0.2
H281DRAFT_03517 -0.5
H281DRAFT_04595 -0.9
H281DRAFT_04625 -0.5
H281DRAFT_06131 -0.2
Acetyl-CoA C-acyltransferase (in reverse):
3-(4-hydroxyphenyl)-3-oxo-propanoyl-CoA + coenzyme A→4-hydroxybenzoyl-CoA + acetyl-CoA (EC 2.3.1.16)
H281DRAFT_00852 -1.6
H281DRAFT_00857 -0.1
H281DRAFT_00917 +0.3
H281DRAFT_01504 +0.1
H281DRAFT_02089 -0.1
H281DRAFT_04626 -0.2
H281DRAFT_05130 N.D.
H281DRAFT_05559 +0.0
H281DRAFT_05723 -5.2
H281DRAFT_06132 +0.1
4-hydroxybenzoyl-CoA thioesterase:
4-hydroxybenzoyl-CoA + H2O→4-hydroxybenzoate + coenzyme A + H+ (EC 3.1.2.23)
H281DRAFT_03699 N.D.

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information