MetaCyc Pathway: 3-phenylpropanoate degradation in Paraburkholderia bryophila 376MFSha3.1

Reactions and Genes	Phenylacetic (C)
3-phenylpropanoate + ATP + coenzyme A→3-phenylpropanoyl-CoA + AMP + diphosphate
No genes
3-phenylpropanoyl-CoA + an oxidized electron carrier→(E)-cinnamoyl-CoA + a reduced two electron carrier
No genes
Enoyl-CoA hydratase (in reverse): (E)-cinnamoyl-CoA + H2O→(S)-3-hydroxy-3-phenylpropanoyl-CoA (EC 4.2.1.17)
H281DRAFT_00361	-1.8
H281DRAFT_00373	-0.2
H281DRAFT_00653	+0.7
H281DRAFT_00756	-0.1
H281DRAFT_00916	-0.2
H281DRAFT_01137	N.D.
H281DRAFT_01179	-0.1
H281DRAFT_01187	+0.1
H281DRAFT_01199	-0.1
H281DRAFT_01200	+0.0
H281DRAFT_01276	+0.5
H281DRAFT_01670	+0.2
H281DRAFT_01774	N.D.
H281DRAFT_02068	-0.5
H281DRAFT_02497	-0.7
H281DRAFT_02514	-0.2
H281DRAFT_02515	N.D.
H281DRAFT_02677	+0.0
H281DRAFT_02741	+0.3
H281DRAFT_02927	+0.2
H281DRAFT_03491	N.D.
H281DRAFT_03701	+0.3
H281DRAFT_03739	+0.1
H281DRAFT_03908	-0.0
H281DRAFT_04594	-5.4
H281DRAFT_04595	-0.9
H281DRAFT_04625	-0.5
H281DRAFT_04627	-0.3
H281DRAFT_04744	-0.1
H281DRAFT_05516	+0.2
H281DRAFT_05722	-6.0
H281DRAFT_05725	-5.8
H281DRAFT_05977	-0.1
3-hydroxyacyl-CoA dehydrogenase: (S)-3-hydroxy-3-phenylpropanoyl-CoA + NAD+→3-oxo-3-phenylpropanoyl-CoA + NADH + H+ (EC 1.1.1.35)
H281DRAFT_00361	-1.8
H281DRAFT_00916	-0.2
H281DRAFT_03517	-0.5
H281DRAFT_04595	-0.9
H281DRAFT_04625	-0.5
H281DRAFT_06131	-0.2
Acetyl-CoA C-acyltransferase (in reverse): 3-oxo-3-phenylpropanoyl-CoA + coenzyme A→benzoyl-CoA + acetyl-CoA (EC 2.3.1.16)
H281DRAFT_00852	-1.6
H281DRAFT_00857	-0.1
H281DRAFT_00917	+0.3
H281DRAFT_01504	+0.1
H281DRAFT_02089	-0.1
H281DRAFT_04626	-0.2
H281DRAFT_05130	N.D.
H281DRAFT_05559	+0.0
H281DRAFT_05723	-5.2
H281DRAFT_06132	+0.1
Benzoyl-CoA 3-monooxygenase: benzoyl-CoA + NADPH + dioxygen + H+→3-hydroxybenzoyl-CoA + NADP+ + H2O (EC 1.14.13.58)
No genes
3-hydroxybenzoyl-CoA + a reduced two electron carrier + dioxygen→gentisate + an oxidized electron carrier + coenzyme A + H+
No genes
Gentisate 1,2-dioxygenase: gentisate + dioxygen→3-maleylpyruvate + H+ (EC 1.13.11.4)
No genes
Maleylpyruvate isomerase: 3-maleylpyruvate→3-fumarylpyruvate (EC 5.2.1.4)
H281DRAFT_01970	-0.1
3-fumarylpyruvate + H2O→fumarate + pyruvate + H+ (EC 3.7.1.20)
H281DRAFT_01971	-0.0

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information