MetaCyc Pathway: L-tyrosine degradation IV (to 4-methylphenol) in Klebsiella michiganensis M5al

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Reactions and Genes L-Leucine (N)
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Aspartate transaminase:
L-tyrosine + 2-oxoglutarate→3-(4-hydroxyphenyl)pyruvate + L-glutamate
(EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
BWI76_RS01925 -0.5
BWI76_RS03690 +0.3
BWI76_RS06660 -0.0
BWI76_RS06750 +0.2
BWI76_RS07560 +0.1
BWI76_RS07570 -0.2
BWI76_RS08675 +0.0
BWI76_RS09870 -0.4
BWI76_RS10245 -0.4
BWI76_RS12985 +0.4
BWI76_RS13400 +0.5
BWI76_RS18930 -6.2
BWI76_RS20205 -1.6
BWI76_RS22035 +0.0
BWI76_RS24235 -1.7
4-hydroxyphenylpyruvate oxidase:
2 3-(4-hydroxyphenyl)pyruvate + dioxygen→2 (4-hydroxyphenyl)acetate + 2 CO2
(EC 1.2.3.13)
No genes
4-hydroxyphenylacetate decarboxylase:
(4-hydroxyphenyl)acetate + H+→4-methylphenol + CO2
(EC 4.1.1.83)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information