MetaCyc Pathway: superpathway of anaerobic energy metabolism (invertebrates) in Klebsiella michiganensis M5al

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Reactions and Genes L-Valine (N)
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Phosphoenolpyruvate carboxykinase (GTP) (in reverse):
phosphoenolpyruvate + CO2 + GDP→oxaloacetate + GTP (EC 4.1.1.32)
No genes
Pyruvate kinase (in reverse):
phosphoenolpyruvate + ADP + H+→pyruvate + ATP (EC 2.7.1.40)
BWI76_RS16960 N.D.
BWI76_RS18115 +0.1
Phosphoenolpyruvate carboxykinase (GTP) (in reverse):
phosphoenolpyruvate + CO2 + IDP→oxaloacetate + ITP (EC 4.1.1.32)
No genes
Alanine transaminase (in reverse):
pyruvate + L-glutamate→2-oxoglutarate + L-alanine (EC 2.6.1.2)
BWI76_RS20205 -0.3
BWI76_RS20495 -1.4
Malate dehydrogenase (in reverse):
oxaloacetate + NADH + H+→(S)-malate + NAD+ (EC 1.1.1.37; 1.1.1.38)
BWI76_RS13830 +0.1
BWI76_RS16775 +0.4
BWI76_RS25420 +0.3
Malate dehydrogenase (oxaloacetate-decarboxylating):
(S)-malate + NAD+→pyruvate + CO2 + NADH (EC 1.1.1.38)
BWI76_RS13830 +0.1
Alanine racemase:
L-alanine→D-alanine (EC 5.1.1.1; 5.1.1.10)
BWI76_RS01920 +0.1
BWI76_RS16300 -0.1
BWI76_RS17730 N.D.
BWI76_RS24285 -2.2
Aspartate transaminase:
2-oxoglutarate + L-aspartate→L-glutamate + oxaloacetate (EC 2.6.1.1)
BWI76_RS03690 +0.1
BWI76_RS06660 -0.0
BWI76_RS06750 +0.2
BWI76_RS07560 -0.1
BWI76_RS07570 +0.1
BWI76_RS08675 +0.1
BWI76_RS09870 -0.3
BWI76_RS10245 -0.1
BWI76_RS12985 -0.1
BWI76_RS13400 +0.1
BWI76_RS20205 -0.3
BWI76_RS22035 +0.1
BWI76_RS24235 -1.3
Fumarate hydratase:
(S)-malate→fumarate + H2O (EC 4.2.1.2)
BWI76_RS08450 +0.0
BWI76_RS16115 +0.1
BWI76_RS16270 +0.1
BWI76_RS16275 -0.5
BWI76_RS16955 -0.6
pyruvate + coenzyme A + NAD+→CO2 + acetyl-CoA + NADH (EC 1.2.1.104)
BWI76_RS04880 N.D.
BWI76_RS04885 N.D.
BWI76_RS04890 N.D.
Succinate dehydrogenase (ubiquinone) (in reverse):
fumarate[in] + a rhodoquinol→succinate[in] + a rhodoquinone (EC 1.3.5.1)
No genes
acetyl-CoA + succinate→acetate + succinyl-CoA (EC 2.8.3.18)
No genes
succinate + propanoyl-CoA→succinyl-CoA + propanoate (EC 2.8.3.27)
BWI76_RS23950 +0.0
Methylmalonyl-CoA mutase (in reverse):
succinyl-CoA→(R)-methylmalonyl-CoA (EC 5.4.99.2)
BWI76_RS23935 -0.1
Succinate--CoA ligase (ADP-forming) (in reverse):
succinyl-CoA + ADP + phosphate→succinate + ATP + coenzyme A (EC 6.2.1.5)
BWI76_RS08425 +0.1
BWI76_RS08430 +0.1
Methylmalonyl-CoA epimerase:
(R)-methylmalonyl-CoA→(S)-methylmalonyl-CoA (EC 5.1.99.1)
No genes
Propionyl-CoA carboxylase (in reverse):
(S)-methylmalonyl-CoA + ADP + H+ + phosphate→propanoyl-CoA + ATP + hydrogen carbonate (EC 6.4.1.3)
BWI76_RS05295 N.D.
BWI76_RS20370 N.D.

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information