MetaCyc Pathway: superpathway of L-aspartate and L-asparagine biosynthesis in Klebsiella michiganensis M5al

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Reactions and Genes L-Proline (N)
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Aspartate transaminase (in reverse):
oxaloacetate + L-glutamate→L-aspartate + 2-oxoglutarate (EC 2.6.1.1)
BWI76_RS03690 +0.1
BWI76_RS06660 -0.0
BWI76_RS06750 +0.0
BWI76_RS07560 +0.3
BWI76_RS07570 +0.1
BWI76_RS08675 +0.0
BWI76_RS09870 -0.5
BWI76_RS10245 -0.4
BWI76_RS12985 -0.0
BWI76_RS13400 +0.1
BWI76_RS20205 -0.3
BWI76_RS22035 +0.1
BWI76_RS24235 +0.1
Aspartate ammonia-lyase (in reverse):
fumarate + ammonium→L-aspartate (EC 4.3.1.1)
BWI76_RS02330 -2.5
Aspartate--ammonia ligase:
L-aspartate + ammonium + ATP→L-asparagine + AMP + diphosphate + H+ (EC 6.3.1.1)
BWI76_RS00250 +0.2
BWI76_RS08180 -4.2
Asparaginase:
L-asparagine + H2O→L-aspartate + ammonium (EC 3.5.1.1; 3.5.1.38; 3.5.5.4)
BWI76_RS11360 +0.1
BWI76_RS11580 -0.3
BWI76_RS14950 -0.6

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information