MetaCyc Pathway: C4 photosynthetic carbon assimilation cycle, PEPCK type in Klebsiella michiganensis M5al

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Reactions and Genes L-Threonine (N)
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Carbonate dehydratase (in reverse):
CO2 + H2O→hydrogen carbonate + H+ (EC 4.2.1.1)
BWI76_RS04960 -0.3
BWI76_RS16635 -0.4
BWI76_RS25560 -0.2
Phosphoenolpyruvate carboxylase (in reverse):
hydrogen carbonate + phosphoenolpyruvate→oxaloacetate + phosphate (EC 4.1.1.31)
BWI76_RS00835 -2.5
Aspartate transaminase (in reverse):
oxaloacetate + L-glutamate→L-aspartate + 2-oxoglutarate (EC 2.6.1.1)
BWI76_RS03690 +0.3
BWI76_RS06660 +0.1
BWI76_RS06750 +0.8
BWI76_RS07560 +0.3
BWI76_RS07570 -0.0
BWI76_RS08675 -0.1
BWI76_RS09870 -1.2
BWI76_RS10245 -0.6
BWI76_RS12985 -0.7
BWI76_RS13400 +0.6
BWI76_RS20205 +0.2
BWI76_RS22035 +0.2
BWI76_RS24235 +0.2
Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)) (in reverse):
oxaloacetate + NADPH + H+→(S)-malate + NADP+ (EC 1.1.1.40; 1.1.1.82)
BWI76_RS20830 -0.1
L-aspartate[in]→L-aspartate[out]
No genes
(S)-malate[in]→(S)-malate[out]
No genes
Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)):
(S)-malate + NADP+→CO2 + pyruvate + NADPH (EC 1.1.1.40)
BWI76_RS20830 -0.1
Aspartate transaminase:
L-aspartate + 2-oxoglutarate→oxaloacetate + L-glutamate (EC 2.6.1.1)
BWI76_RS03690 +0.3
BWI76_RS06660 +0.1
BWI76_RS06750 +0.8
BWI76_RS07560 +0.3
BWI76_RS07570 -0.0
BWI76_RS08675 -0.1
BWI76_RS09870 -1.2
BWI76_RS10245 -0.6
BWI76_RS12985 -0.7
BWI76_RS13400 +0.6
BWI76_RS20205 +0.2
BWI76_RS22035 +0.2
BWI76_RS24235 +0.2
Alanine transaminase (in reverse):
pyruvate + L-glutamate→L-alanine + 2-oxoglutarate (EC 2.6.1.2)
BWI76_RS20205 +0.2
BWI76_RS20495 -1.4
Phosphoenolpyruvate carboxykinase (ATP):
oxaloacetate + ATP→CO2 + phosphoenolpyruvate + ADP (EC 4.1.1.49)
BWI76_RS17605 +0.2
BWI76_RS26155 +0.2
L-alanine[in]→L-alanine[out]
No genes
phosphoenolpyruvate[in]→phosphoenolpyruvate[out]
No genes
Alanine transaminase (in reverse):
L-alanine + 2-oxoglutarate→pyruvate + L-glutamate (EC 2.6.1.2)
BWI76_RS20205 +0.2
Pyruvate, phosphate dikinase:
pyruvate + ATP + phosphate→phosphoenolpyruvate + AMP + diphosphate + H+ (EC 2.7.9.1)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information