MetaCyc Pathway: L-arginine degradation II (AST pathway) in Klebsiella michiganensis M5al

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Reactions and Genes L-Lysine (N)
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Arginine N-succinyltransferase:
L-arginine + succinyl-CoA→N2-succinyl-L-arginine + coenzyme A + H+ (EC 2.3.1.109)
BWI76_RS11675 -7.0
N-succinylarginine dihydrolase:
N2-succinyl-L-arginine + 2 H+ + 2 H2O→N2-succinyl-L-ornithine + 2 ammonium + CO2 (EC 3.5.3.23)
BWI76_RS11685 +0.2
Succinylornithine transaminase:
N2-succinyl-L-ornithine + 2-oxoglutarate→N2-succinyl-L-glutamate 5-semialdehyde + L-glutamate (EC 2.6.1.81)
BWI76_RS11670 -3.9
BWI76_RS26000 +1.0
Succinylglutamate-semialdehyde dehydrogenase:
N2-succinyl-L-glutamate 5-semialdehyde + NAD+ + H2O→N2-succinylglutamate + NADH + 2 H+ (EC 1.2.1.71)
BWI76_RS11680 -2.7
Succinylglutamate desuccinylase:
N2-succinylglutamate + H2O→L-glutamate + succinate (EC 3.5.1.96)
BWI76_RS11690 -2.0

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information