MetaCyc Pathway: superpathway of L-tyrosine biosynthesis in Pseudomonas stutzeri RCH2

Reactions and Genes	Def Chlorate 20 mM
3-deoxy-7-phosphoheptulonate synthase: D-erythrose 4-phosphate + phosphoenolpyruvate + H2O→3-deoxy-D-arabino-heptulosonate 7-phosphate + phosphate (EC 2.5.1.54)
Psest_1801	-1.3
Psest_2331	-2.3
Psest_3030	-3.4
3-dehydroquinate synthase: 3-deoxy-D-arabino-heptulosonate 7-phosphate→3-dehydroquinate + phosphate (EC 4.2.3.4)
Psest_3713	N.D.
3-dehydroquinate dehydratase: 3-dehydroquinate→3-dehydroshikimate + H2O (EC 4.2.1.10)
Psest_2822	N.D.
Psest_1021	N.D.
Shikimate dehydrogenase (in reverse): 3-dehydroshikimate + NADPH + H+→shikimate + NADP+ (EC 1.1.1.25)
Psest_0029	N.D.
Shikimate kinase: shikimate + ATP→shikimate 3-phosphate + ADP + H+ (EC 2.7.1.71)
Psest_3714	N.D.
3-phosphoshikimate 1-carboxyvinyltransferase: shikimate 3-phosphate + phosphoenolpyruvate→5-enolpyruvoyl-shikimate 3-phosphate + phosphate (EC 2.5.1.19)
Psest_1986	+0.3
Chorismate synthase: 5-enolpyruvoyl-shikimate 3-phosphate→chorismate + phosphate (EC 4.2.3.5)
Psest_1903	N.D.
Chorismate mutase: chorismate→prephenate (EC 5.4.99.5)
Psest_1984	N.D.
Prephenate dehydrogenase: prephenate + NAD+→3-(4-hydroxyphenyl)pyruvate + CO2 + NADH (EC 1.3.1.12)
Psest_1986	+0.3
Aspartate transaminase (in reverse): 3-(4-hydroxyphenyl)pyruvate + L-glutamate→L-tyrosine + 2-oxoglutarate (EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
Psest_1268	+0.3
Psest_1295	-2.3
Psest_1570	+0.5
Psest_1710	+0.4
Psest_1985	-0.2
Psest_1990	-0.0
Psest_3297	-2.0
Psest_0779	+0.6

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information