MetaCyc Pathway: CMP-pseudaminate biosynthesis in Pseudomonas stutzeri RCH2

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Reactions and Genes Def Chlorate 20 mM
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UDP-N-acetylglucosamine 4,6-dehydratase (inverting):
UDP-N-acetyl-α-D-glucosamine→UDP-2-acetamido-2,6-dideoxy-β-L-arabino-hex-4-ulose + H2O
(EC 4.2.1.115)
Psest_1810 +1.5
UDP-2-acetamido-2,6-dideoxy-β-L-arabino-hex-4-ulose + L-glutamate→UDP-4-amino-4,6-dideoxy-N-acetyl-β-L-altrosamine + 2-oxoglutarate (EC 2.6.1.92)
Psest_1811 N.D.
UDP-4-amino-4,6-dideoxy-N-acetyl-β-L-altrosamine + acetyl-CoA→UDP-2,4-diacetamido-2,4,6-trideoxy-β-L-altropyranose + coenzyme A + H+ (EC 2.3.1.202)
Psest_1814 +0.3
UDP-2,4-diacetamido-2,4,6-trideoxy-β-L-altropyranose + H2O→2,4-diacetamido-2,4,6-trideoxy-β-L-altropyranose + H+ + UDP (EC 3.6.1.57)
Psest_1813 -0.4
2,4-diacetamido-2,4,6-trideoxy-β-L-altropyranose + phosphoenolpyruvate + H2O→pseudaminate + phosphate (EC 2.5.1.97)
Psest_1815 -0.7
pseudaminate + CTP→CMP-pseudaminate + diphosphate (EC 2.7.7.81)
Psest_1812 -0.4

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information