MetaCyc Pathway: γ-linolenate biosynthesis II (animals) in Mycobacterium tuberculosis H37Rv

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Reactions and Genes cholesterol 100uM (C)
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Long-chain-fatty-acid--CoA ligase:
linoleate + ATP + coenzyme A→linoleoyl-CoA + AMP + diphosphate (EC 6.2.1.3)
Rv0166 +0.2
Rv0214 +0.0
Rv0270 +0.5
Rv1013 -0.6
Rv1058 +0.2
Rv1427c +0.2
Rv2187 +0.1
Rv2505c +0.3
Rv3506 +0.1
Rv3513c -3.6
Rv3515c -0.2
Rv3561 -1.6
Linoleoyl-CoA desaturase:
linoleoyl-CoA + 2 a ferrocytochrome b5 + dioxygen + 2 H+→γ-linolenoyl-CoA + 2 a ferricytochrome b5 + 2 H2O (EC 1.14.19.3)
Rv3229c +1.6

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information