MetaCyc Pathway: fatty acid β-oxidation I (generic) in Dinoroseobacter shibae DFL-12

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Reactions and Genes m.b. Benzalkonium Chloride 0.0005 mg/ml
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a 2,3,4-saturated fatty acid + ATP + coenzyme A→a 2,3,4-saturated fatty acyl CoA + AMP + diphosphate
No genes
Dodecenoyl-CoA isomerase:
a (3Z)-3-enoyl-CoA→a (2E)-2-enoyl-CoA
(EC 5.3.3.8)
Dshi_3826 -0.2
3-hydroxybutyryl-CoA epimerase:
a 2,3,4-saturated (3R)-3-hydroxyacyl-CoA→a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA
(EC 5.1.2.3)
Dshi_0835 +0.1
Dshi_3826 -0.2
a 2,3,4-saturated fatty acyl CoA + an oxidized electron-transfer flavoprotein + H+→a (2E)-2-enoyl-CoA + a reduced electron-transfer flavoprotein
No genes
Enoyl-CoA hydratase (in reverse):
a (2E)-2-enoyl-CoA + H2O→a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA
(EC 4.2.1.17)
Dshi_0067 +0.0
Dshi_0835 +0.1
Dshi_1048 -0.0
Dshi_1604 -0.0
Dshi_1751 -0.2
Dshi_1753 -4.5
Dshi_3329 +0.2
Dshi_3370 N.D.
Dshi_3826 -0.2
3-hydroxyacyl-CoA dehydrogenase:
a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA + NAD+→a 2,3,4-saturated 3-oxoacyl-CoA + NADH + H+
(EC 1.1.1.35)
Dshi_0835 +0.1
Dshi_1700 +0.2
Dshi_2825 -0.0
Dshi_3826 -0.2
Acetyl-CoA C-acyltransferase (in reverse):
a 2,3,4-saturated 3-oxoacyl-CoA + coenzyme A→a 2,3,4-saturated fatty acyl CoA + acetyl-CoA
(EC 2.3.1.16)
Dshi_0074 +0.0
Dshi_0836 -0.2
Dshi_3066 +0.5
Dshi_3331 +0.0
Dshi_3817 +0.4

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information