MetaCyc Pathway: superpathway of NAD/NADP - NADH/NADPH interconversion (yeast) in Pseudomonas fluorescens FW300-N2E2

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Reactions and Genes dimethyl sulfone 0.25 M
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NAD(+) kinase:
NAD+ + ATP→NADP+ + ADP + H+
(EC 2.7.1.23; 2.7.1.M29)
Pf6N2E2_599 N.D.
Aldehyde dehydrogenase (NADP(+)):
NADP+ + an aldehyde + H2O→NADPH + a carboxylate + 2 H+
(EC 1.2.1.4)
Pf6N2E2_612 -0.0
Pf6N2E2_859 +0.1
Aldehyde dehydrogenase (NAD(+)):
NAD+ + an aldehyde + H2O→NADH + a carboxylate + 2 H+
(EC 1.2.1.3)
Pf6N2E2_1381 +0.4
Pf6N2E2_1764 +0.1
Pf6N2E2_1854 -0.1
Pf6N2E2_1874 N.D.
Pf6N2E2_1878 -0.1
Pf6N2E2_1906 +0.0
Pf6N2E2_1919 -0.1
Pf6N2E2_225 -0.4
Pf6N2E2_3298 +0.5
Pf6N2E2_351 +0.3
Pf6N2E2_3582 +0.1
Pf6N2E2_4383 -0.1
Pf6N2E2_4964 -0.1
Pf6N2E2_4979 -0.1
Pf6N2E2_5476 -0.3
Pf6N2E2_935 +0.1
Glucose-6-phosphate dehydrogenase:
NADP+ + D-glucopyranose 6-phosphate→NADPH + 6-phospho D-glucono-1,5-lactone + H+
(EC 1.1.1.49)
Pf6N2E2_2885 -0.3
Pf6N2E2_758 -0.1
Isocitrate dehydrogenase (NADP(+)):
NADP+ + D-threo-isocitrate→NADPH + 2-oxoglutarate + CO2
(EC 1.1.1.42)
Pf6N2E2_288 +0.3
Pf6N2E2_289 -0.4
Aldehyde dehydrogenase (NADP(+)):
NADP+ + acetaldehyde + H2O→NADPH + acetate + 2 H+
(EC 1.2.1.4)
Pf6N2E2_612 -0.0
Pf6N2E2_859 +0.1
NADH kinase:
NADH + ATP→NADPH + ADP + H+
(EC 2.7.1.86; 2.7.1.M29)
No genes
NADH[in] + H+[in] + a ubiquinone→NAD+[in] + a ubiquinol (EC 1.6.5.9)
Pf6N2E2_5132 -3.3
Pf6N2E2_594 -0.2

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information