MetaCyc Pathway: L-tyrosine degradation IV (to 4-methylphenol) in Pseudomonas fluorescens FW300-N2C3

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Reactions and Genes L-Isoleucine (N)
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Aspartate transaminase:
L-tyrosine + 2-oxoglutarate→3-(4-hydroxyphenyl)pyruvate + L-glutamate (EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
AO356_01275 +0.4
AO356_03090 -0.2
AO356_03460 -0.4
AO356_03985 -0.1
AO356_06565 +0.0
AO356_06960 -1.7
AO356_12070 +0.1
AO356_12595 +0.2
AO356_16875 -0.1
AO356_19495 -0.0
AO356_19865 +0.2
AO356_19905 +0.0
AO356_20345 -1.7
AO356_21330 -2.4
AO356_22880 -0.0
AO356_24005 -0.0
AO356_24115 -0.0
AO356_24720 +0.1
AO356_24975 +0.1
AO356_25355 +0.1
4-hydroxyphenylpyruvate oxidase:
2 3-(4-hydroxyphenyl)pyruvate + dioxygen→2 (4-hydroxyphenyl)acetate + 2 CO2 (EC 1.2.3.13)
No genes
4-hydroxyphenylacetate decarboxylase:
(4-hydroxyphenyl)acetate + H+→4-methylphenol + CO2 (EC 4.1.1.83)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information