MetaCyc Pathway: superpathway of phospholipid biosynthesis III (E. coli) in Pseudomonas fluorescens FW300-N2E2

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Reactions and Genes sodium iodate 0.005 M
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Glycerol-3-phosphate dehydrogenase (NAD(P)(+)) (in reverse):
glycerone phosphate + NAD(P)H + H+→sn-glycerol 3-phosphate + NAD(P)+ (EC 1.1.1.94)
Pf6N2E2_5875 N.D.
Glycerol-3-phosphate O-acyltransferase:
sn-glycerol 3-phosphate + an acyl-[acyl-carrier protein]→a 2-lysophosphatidate + a soluble [acyl-carrier protein] (EC 2.3.1.15)
Pf6N2E2_3087 -1.0
Pf6N2E2_4795 +0.7
Pf6N2E2_5950 +0.3
Glycerol-3-phosphate O-acyltransferase:
sn-glycerol 3-phosphate + an acyl-CoA→a 2-lysophosphatidate + coenzyme A (EC 2.3.1.15)
Pf6N2E2_3087 -1.0
Pf6N2E2_4795 +0.7
Pf6N2E2_5950 +0.3
1-acylglycerol-3-phosphate O-acyltransferase:
a 2-lysophosphatidate + an acyl-[acyl-carrier protein]→a phosphatidate + a soluble [acyl-carrier protein] (EC 2.3.1.51)
Pf6N2E2_2816 N.D.
Pf6N2E2_4192 N.D.
Pf6N2E2_4950 +0.5
Pf6N2E2_5765 -0.0
Pf6N2E2_6003 +0.2
1-acylglycerol-3-phosphate O-acyltransferase:
a 2-lysophosphatidate + an acyl-CoA→a phosphatidate + coenzyme A (EC 2.3.1.51)
Pf6N2E2_2816 N.D.
Pf6N2E2_4192 N.D.
Pf6N2E2_4950 +0.5
Pf6N2E2_5765 -0.0
Pf6N2E2_6003 +0.2
Phosphatidate cytidylyltransferase:
a phosphatidate + CTP + H+→a CDP-diacylglycerol + diphosphate (EC 2.7.7.41)
Pf6N2E2_3064 N.D.
Pf6N2E2_4949 -0.0
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase:
a CDP-diacylglycerol + sn-glycerol 3-phosphate→a phosphatidylglycerophosphate + CMP + H+ (EC 2.7.8.5)
Pf6N2E2_2020 N.D.
Pf6N2E2_4954 -0.0
CDP-diacylglycerol--serine O-phosphatidyltransferase:
a CDP-diacylglycerol + L-serine→a phosphatidylserine + CMP + H+ (EC 2.7.8.8)
Pf6N2E2_1137 -0.1
Pf6N2E2_5178 -3.0
Phosphatidylglycerophosphatase:
a phosphatidylglycerophosphate + H2O→a phosphatidylglycerol + phosphate (EC 3.1.3.27)
Pf6N2E2_4925 N.D.
Phosphatidylserine decarboxylase:
a phosphatidylserine + H+→a phosphatidylethanolamine + CO2 (EC 4.1.1.65)
Pf6N2E2_3628 N.D.
2 a phosphatidylglycerol→a cardiolipin + glycerol (EC 2.7.8.41)
Pf6N2E2_4901 -0.0
a phosphatidylethanolamine + a phosphatidylglycerol→a cardiolipin + ethanolamine (EC 2.7.8.41)
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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information