MetaCyc Pathway: L-glutamate and L-glutamine biosynthesis in Sphingomonas koreensis DSMZ 15582

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Reactions and Genes L-Glutamine (N)
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Glutamate dehydrogenase (NAD(P)(+)) (in reverse):
2-oxoglutarate + ammonium + NAD(P)H + H+→L-glutamate + NAD(P)+ + H2O (EC 1.4.1.3)
No genes
Glutamate synthase (ferredoxin) (in reverse):
2-oxoglutarate + L-glutamine + 2 H+ + 2 a reduced ferredoxin [iron-sulfur] cluster→2 L-glutamate + 2 an oxidized ferredoxin [iron-sulfur] cluster (EC 1.4.7.1)
No genes
Glutamate synthase (NADH) (in reverse):
2-oxoglutarate + L-glutamine + NADH + H+→2 L-glutamate + NAD+ (EC 1.4.1.14)
Ga0059261_1797 -4.0
Glutamate synthase (NADPH):
L-glutamine + H2O→L-glutamate + ammonia + H+ (EC 1.4.1.13; 1.4.1.14; 1.4.7.1; 2.6.1.85; 3.5.1.2; 3.5.1.38; 4.1.3.27; 4.3.2.10; 4.3.3.6; 6.3.4.2; 6.3.5.13; 6.3.5.2; 6.3.5.4; 6.3.5.5; 6.3.5.6; 6.3.5.7)
Ga0059261_0006 N.D.
Ga0059261_0007 N.D.
Ga0059261_0081 N.D.
Ga0059261_0082 N.D.
Ga0059261_0083 -0.4
Ga0059261_0256 -4.6
Ga0059261_0317 N.D.
Ga0059261_0347 N.D.
Ga0059261_0838 +0.1
Ga0059261_0926 -5.3
Ga0059261_1487 +3.8
Ga0059261_1797 -4.0
Ga0059261_1800 -4.1
Ga0059261_2227 +0.4
Ga0059261_3119 -3.7
Ga0059261_3121 -2.3
Ga0059261_4199 +0.5
Ga0059261_4243 N.D.
Glutamate--ammonia ligase:
L-glutamate + ammonium + ATP→L-glutamine + ADP + H+ + phosphate (EC 6.3.1.2)
Ga0059261_3384 N.D.
Glutamate dehydrogenase (NADP(+)) (in reverse):
2-oxoglutarate + ammonium + NADPH + H+→L-glutamate + NADP+ + H2O (EC 1.4.1.4)
No genes
Glutamate synthase (NADPH) (in reverse):
2-oxoglutarate + ammonia + NADPH + 2 H+→L-glutamate + NADP+ + H2O (EC 1.4.1.13; 1.4.1.14)
Ga0059261_1797 -4.0
Ga0059261_1800 -4.1

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information