MetaCyc Pathway: L-tryptophan degradation XIII (reductive Stickland reaction) in Bifidobacterium breve UCC2003

Add experiment(s):


Reactions and Genes Recovery broth with Serine hydroxamate 11 mM
remove
Aspartate transaminase:
L-tryptophan + 2-oxoglutarate→(indol-3-yl)pyruvate + L-glutamate
(EC 2.6.1.1; 2.6.1.27)
BBR_RS13205 -1.9
BBR_RS13460 +0.0
BBR_RS14535 +0.4
BBR_RS15505 -1.0
BBR_RS15560 +0.5
BBR_RS17345 +0.1
BBR_RS17965 -0.0
BBR_RS19435 -2.6
Indolelactate dehydrogenase (in reverse):
(indol-3-yl)pyruvate + NADH + H+→(R)-3-(indol-3-yl)lactate + NAD+
(EC 1.1.1.110)
No genes
Cinnamoyl-CoA:phenyllactate CoA-transferase:
(R)-3-(indol-3-yl)lactate + 3-(indol-3-yl)acryloyl-CoA→3-(indol-3-yl)acrylate + (R)-3-(indol-3-yl)lactoyl-CoA
(EC 2.8.3.17)
No genes
3-(indol-3-yl)acrylate + a reduced electron-transfer flavoprotein→3-(1H-indol-3-yl)propanoate + an oxidized electron-transfer flavoprotein + H+ (EC 1.3.8.15)
No genes
(R)-3-(indol-3-yl)lactoyl-CoA→3-(indol-3-yl)acryloyl-CoA + H2O (EC 4.2.1.175)
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information