MetaCyc Pathway: 4-hydroxybenzoate biosynthesis I (eukaryotes) in Bifidobacterium breve UCC2003

Add experiment(s):


Reactions and Genes Recovery broth with Serine hydroxamate 11 mM
remove
Aspartate transaminase:
L-tyrosine + 2-oxoglutarate→3-(4-hydroxyphenyl)pyruvate + L-glutamate (EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
BBR_RS13205 -1.9
BBR_RS13460 +0.0
BBR_RS14535 +0.4
BBR_RS15505 -1.0
BBR_RS15560 +0.5
BBR_RS17050 -0.1
BBR_RS17345 +0.1
BBR_RS17965 -0.0
BBR_RS19435 -2.6
Indolelactate dehydrogenase (in reverse):
3-(4-hydroxyphenyl)pyruvate + NADH + H+→(R)-3-(4-hydroxyphenyl)lactate + NAD+ (EC 1.1.1.110)
No genes
Cinnamoyl-CoA:phenyllactate CoA-transferase:
(R)-3-(4-hydroxyphenyl)lactate + (E)-4-coumaroyl-CoA→4-coumarate + (R)-3-(4-hydroxyphenyl)lactoyl-CoA (EC 2.8.3.17)
No genes
4-coumarate + H2O→4-hydroxybenzaldehyde + acetate
No genes
4-hydroxybenzaldehyde dehydrogenase:
4-hydroxybenzaldehyde + NAD+ + H2O→4-hydroxybenzoate + NADH + 2 H+ (EC 1.2.1.64)
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information