MetaCyc Pathway: L-histidine degradation I in Shewanella loihica PV-4

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Reactions and Genes Fusidic 0.0625 mg/ml
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Histidine ammonia-lyase:
L-histidine→urocanate + ammonium (EC 4.3.1.3)
Shew_2280 +0.2
Shew_3517 +6.8
Shew_3756 -0.6
Urocanate hydratase (in reverse):
urocanate + H2O→4-imidazolone-5-propanoate (EC 4.2.1.49)
Shew_3757 -0.3
Imidazolonepropionase:
4-imidazolone-5-propanoate + H2O→N-formimino-L-glutamate (EC 3.5.2.7)
Shew_3759 +1.1
Formimidoylglutamase:
N-formimino-L-glutamate + H2O→L-glutamate + formamide (EC 3.5.3.8)
Shew_3372 -0.2

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information