MetaCyc Pathway: superpathway of L-phenylalanine biosynthesis in Pseudomonas fluorescens FW300-N1B4

Add experiment(s):


Reactions and Genes L-Serine (N)
remove
3-deoxy-7-phosphoheptulonate synthase:
D-erythrose 4-phosphate + phosphoenolpyruvate + H2O→3-deoxy-D-arabino-heptulosonate 7-phosphate + phosphate (EC 2.5.1.54)
Pf1N1B4_269 -0.1
Pf1N1B4_289 +0.2
Pf1N1B4_5622 +0.4
3-dehydroquinate synthase:
3-deoxy-D-arabino-heptulosonate 7-phosphate→3-dehydroquinate + phosphate (EC 4.2.3.4)
Pf1N1B4_1537 N.D.
3-dehydroquinate dehydratase:
3-dehydroquinate→3-dehydroshikimate + H2O (EC 4.2.1.10)
Pf1N1B4_1307 -4.3
Pf1N1B4_2750 +0.0
Pf1N1B4_3104 N.D.
Shikimate dehydrogenase (in reverse):
3-dehydroshikimate + NADPH + H+→shikimate + NADP+ (EC 1.1.1.25)
Pf1N1B4_1906 -2.6
Pf1N1B4_2749 -0.1
Pf1N1B4_3930 -0.3
Shikimate kinase:
shikimate + ATP→shikimate 3-phosphate + ADP + H+ (EC 2.7.1.71)
Pf1N1B4_1538 N.D.
3-phosphoshikimate 1-carboxyvinyltransferase:
shikimate 3-phosphate + phosphoenolpyruvate→5-enolpyruvoyl-shikimate 3-phosphate + phosphate (EC 2.5.1.19)
Pf1N1B4_348 +0.1
Chorismate synthase:
5-enolpyruvoyl-shikimate 3-phosphate→chorismate + phosphate (EC 4.2.3.5)
Pf1N1B4_3780 N.D.
Chorismate mutase:
chorismate→prephenate (EC 5.4.99.5)
Pf1N1B4_350 -2.7
Prephenate dehydratase:
prephenate + H+→3-phenyl-2-oxopropanoate + CO2 + H2O (EC 4.2.1.51)
Pf1N1B4_350 -2.7
Pf1N1B4_54 -0.1
Aspartate transaminase (in reverse):
3-phenyl-2-oxopropanoate + L-glutamate→L-phenylalanine + 2-oxoglutarate (EC 2.6.1.1; 2.6.1.27; 2.6.1.57)
Pf1N1B4_1065 -0.3
Pf1N1B4_160 -0.0
Pf1N1B4_2018 +0.0
Pf1N1B4_2139 +0.0
Pf1N1B4_261 +0.0
Pf1N1B4_27 -2.0
Pf1N1B4_349 -0.4
Pf1N1B4_3564 -0.1
Pf1N1B4_3771 -0.3
Pf1N1B4_386 -1.2
Pf1N1B4_4186 -0.1
Pf1N1B4_4425 -0.2
Pf1N1B4_4646 -0.1
Pf1N1B4_4672 N.D.
Pf1N1B4_4996 +0.0
Pf1N1B4_5070 +0.1
Pf1N1B4_510 -0.3
Pf1N1B4_5999 +0.2
Pf1N1B4_818 -0.0
Pf1N1B4_849 +0.1

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information