MetaCyc Pathway: superpathway of 2,3-butanediol biosynthesis in Klebsiella michiganensis M5al

Reactions and Genes	D-Lactate (C)
Acetolactate synthase: 2 pyruvate + H+→(S)-2-acetolactate + CO2 (EC 2.2.1.6)
BWI76_RS00960	-1.1
BWI76_RS00965	-2.0
BWI76_RS04695	+0.0
BWI76_RS04700	+0.1
BWI76_RS12900	-0.3
BWI76_RS16750	+0.2
BWI76_RS27810	-1.1
BWI76_RS27815	-2.7
(R)-acetoin + NADH + H+→(R,S)-2,3-butanediol + NAD+
BWI76_RS16755	-0.0
BWI76_RS23630	+0.1
(S)-2-acetolactate + an oxidized electron carrier + H+→CO2 + diacetyl + a reduced two electron carrier (spontaneous)
No genes
diacetyl + NADH + H+→(S)-acetoin + NAD+ (EC 1.1.1.304)
BWI76_RS16755	-0.0
BWI76_RS23630	+0.1
(S)-acetoin + NADH + H+→(R,S)-2,3-butanediol + NAD+
No genes
(S,S)-butanediol dehydrogenase (in reverse): (S)-acetoin + NADH + H+→(S,S)-2,3-butanediol + NAD+ (EC 1.1.1.76)
BWI76_RS23630	+0.1

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information