MetaCyc Pathway: glutathione-mediated detoxification II in Pseudomonas fluorescens FW300-N2E3

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Reactions and Genes outer cut, LB soft agar motility assay
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Glutathione transferase:
RX + glutathione→a glutathione-S-conjugate + HX (EC 2.5.1.18)
AO353_00030 +0.3
AO353_01700 -0.1
AO353_03280 +0.2
AO353_03665 +0.1
AO353_04575 -0.1
AO353_05750 +0.3
AO353_09005 -0.5
AO353_10285 -0.4
AO353_14715 -0.3
AO353_15560 -2.2
AO353_21320 -0.3
AO353_27620 +0.1
AO353_28505 -0.0
a glutathione-S-conjugate[in] + ATP[in] + H2O[in]→a glutathione-S-conjugate[out] + ADP[in] + H+[in] + phosphate[in] (EC 7.6.2.3)
No genes
a glutathione-S-conjugate + H2O→a [γ-glutamyl-L-cysteine]-S-conjugate + glycine (EC 3.4.17.25)
No genes
a glutathione-S-conjugate + H2O→an (L-cysteinylglycine)-S-conjugate + L-glutamate (EC 3.4.19.13)
No genes
a [γ-glutamyl-L-cysteine]-S-conjugate + H2O→an L-cysteine-S-conjugate + L-glutamate (EC 3.4.13.M2)
No genes
an (L-cysteinylglycine)-S-conjugate + H2O→an L-cysteine-S-conjugate + glycine (EC 3.4.13.23)
No genes
an L-cysteine-S-conjugate + malonyl-CoA→an N-malonyl-L-cysteine-S-conjugate + coenzyme A + H+
No genes
Cysteine-S-conjugate beta-lyase:
an L-cysteine-S-conjugate + H2O→a thiol + ammonium + pyruvate (EC 4.4.1.13)
AO353_24330 +0.3
Thiol S-methyltransferase:
a thiol + S-adenosyl-L-methionine→a methyl thioether + S-adenosyl-L-homocysteine + H+ (EC 2.1.1.9)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information