MetaCyc Pathway: 1,3-propanediol biosynthesis (engineered) in Klebsiella michiganensis M5al

Add experiment(s):


Reactions and Genes a-Cyclodextrin (C)
remove
D-glucose[out] + H+[out]→D-glucose[in] + H+[in]
BWI76_RS24055 -0.1
Hexokinase:
D-glucopyranose + ATP→D-glucopyranose 6-phosphate + ADP + H+ (EC 2.7.1.1; 2.7.1.2)
BWI76_RS20510 -2.7
Glucose-6-phosphate isomerase:
α-D-glucose 6-phosphate→β-D-fructofuranose 6-phosphate (EC 5.3.1.9)
BWI76_RS01800 -2.9
6-phosphofructokinase:
β-D-fructofuranose 6-phosphate + ATP→β-D-fructofuranose 1,6-bisphosphate + ADP + H+ (EC 2.7.1.11)
BWI76_RS00530 +0.1
BWI76_RS00735 N.D.
BWI76_RS17175 N.D.
Fructose-bisphosphate aldolase:
β-D-fructofuranose 1,6-bisphosphate→glycerone phosphate + D-glyceraldehyde 3-phosphate (EC 4.1.2.13)
BWI76_RS00545 +0.1
BWI76_RS14880 -0.1
BWI76_RS19370 +0.0
BWI76_RS23975 N.D.
BWI76_RS27560 +0.1
Glycerol-3-phosphate dehydrogenase (NAD(+)) (in reverse):
glycerone phosphate + NADH + H+→sn-glycerol 3-phosphate + NAD+ (EC 1.1.1.8)
BWI76_RS27210 N.D.
Glycerol-1-phosphatase:
sn-glycerol 3-phosphate + H2O→glycerol + phosphate (EC 3.1.3.21)
No genes
Glycerol dehydratase:
glycerol→3-hydroxypropanal + H2O (EC 4.2.1.30)
No genes
3-hydroxypropanal + NADPH + H+→1,3-propanediol + NADP+
BWI76_RS24300 -0.3

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information