MetaCyc Pathway: superpathway of glucose and xylose degradation in Klebsiella michiganensis M5al

Add experiment(s):


Reactions and Genes D-Xylose (C)
remove
Glucose-6-phosphate dehydrogenase:
D-glucopyranose 6-phosphate + NADP+→6-phospho D-glucono-1,5-lactone + NADPH + H+ (EC 1.1.1.49)
BWI76_RS18105 N.D.
Xylose isomerase:
α-D-xylopyranose→α-D-xylulofuranose (EC 5.3.1.5)
BWI76_RS27025 -3.7
6-phosphogluconolactonase:
6-phospho D-glucono-1,5-lactone + H2O→D-gluconate 6-phosphate + H+ (EC 3.1.1.31)
BWI76_RS08665 -0.7
Xylulokinase:
D-xylulose + ATP→D-xylulose 5-phosphate + ADP + H+ (EC 2.7.1.17)
BWI76_RS19340 -0.1
BWI76_RS23660 -0.1
BWI76_RS27020 -2.4
Phosphogluconate dehydrogenase (decarboxylating):
D-gluconate 6-phosphate + NADP+→D-ribulose 5-phosphate + CO2 + NADPH (EC 1.1.1.44)
BWI76_RS19025 -0.2
Ribose-5-phosphate isomerase (in reverse):
D-ribulose 5-phosphate→D-ribose 5-phosphate (EC 5.3.1.6)
BWI76_RS02175 +0.2
BWI76_RS23925 N.D.
Ribulose-phosphate 3-epimerase:
D-ribulose 5-phosphate→D-xylulose 5-phosphate (EC 5.1.3.1)
BWI76_RS02150 -0.3
BWI76_RS23675 +0.2
BWI76_RS26070 N.D.
Transketolase (in reverse):
D-ribose 5-phosphate + D-xylulose 5-phosphate→D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate (EC 2.2.1.1)
BWI76_RS07680 -0.2
BWI76_RS07685 N.D.
BWI76_RS08905 +0.4
BWI76_RS08910 -0.1
BWI76_RS09705 -0.0
BWI76_RS09710 -0.4
BWI76_RS20245 -0.2
BWI76_RS20250 +0.1
BWI76_RS20835 +0.1
BWI76_RS24015 N.D.
Transaldolase:
D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate→D-erythrose 4-phosphate + β-D-fructofuranose 6-phosphate (EC 2.2.1.2)
BWI76_RS00820 +0.1
BWI76_RS04270 -1.9
Transketolase:
D-erythrose 4-phosphate + D-xylulose 5-phosphate→β-D-fructofuranose 6-phosphate + D-glyceraldehyde 3-phosphate (EC 2.2.1.1)
BWI76_RS07680 -0.2
BWI76_RS07685 N.D.
BWI76_RS08905 +0.4
BWI76_RS08910 -0.1
BWI76_RS09705 -0.0
BWI76_RS09710 -0.4
BWI76_RS20245 -0.2
BWI76_RS20250 +0.1
BWI76_RS20835 +0.1
BWI76_RS24015 N.D.
Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating):
D-glyceraldehyde 3-phosphate + NAD+ + phosphate→3-phospho-D-glyceroyl phosphate + NADH + H+ (EC 1.2.1.12)
BWI76_RS11505 N.D.
BWI76_RS12975 -0.1
BWI76_RS13215 +0.7
Phosphoglycerate kinase (in reverse):
3-phospho-D-glyceroyl phosphate + ADP→3-phospho-D-glycerate + ATP (EC 2.7.2.3)
BWI76_RS23980 N.D.
3-phospho-D-glycerate→2-phospho-D-glycerate (EC 5.4.2.12)
BWI76_RS04200 -0.2
BWI76_RS08605 +0.2
BWI76_RS13025 -0.1
BWI76_RS27230 -0.0
Phosphopyruvate hydratase:
2-phospho-D-glycerate→phosphoenolpyruvate + H2O (EC 4.2.1.11)
BWI76_RS22790 N.D.
Pyruvate kinase (in reverse):
phosphoenolpyruvate + ADP + H+→pyruvate + ATP (EC 2.7.1.40)
BWI76_RS16960 N.D.
BWI76_RS18115 +0.5
D-lactate dehydrogenase (in reverse):
pyruvate + NADH + H+→(R)-lactate + NAD+ (EC 1.1.1.28)
BWI76_RS12790 +0.6
BWI76_RS19515 +0.3
L-lactate dehydrogenase (in reverse):
pyruvate + NADH + H+→(S)-lactate + NAD+ (EC 1.1.1.27)
BWI76_RS15220 -0.2

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information