MetaCyc Pathway: tetrahydromonapterin biosynthesis in Pseudomonas fluorescens SBW25-INTG

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Reactions and Genes NAG carbon and (N); with MOPS
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GTP cyclohydrolase I:
GTP + H2O→7,8-dihydroneopterin 3'-triphosphate + formate + H+ (EC 3.5.4.16)
PFLU_RS21315 +0.0
PFLU_RS25310 +0.0
PFLU_RS29970 -0.0
7,8-dihydroneopterin 3'-triphosphate→7,8-dihydromonapterin triphosphate (EC 5.1.99.7)
PFLU_RS25315 -2.0
7,8-dihydromonapterin triphosphate + 3 H2O→7,8-dihydromonapterin + 2 H+ + 3 phosphate
No genes
7,8-dihydromonapterin + NADPH + H+→5,6,7,8-tetrahydromonapterin + NADP+ (EC 1.5.1.50)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information