MetaCyc Pathway: L-lysine degradation X in Pseudomonas fluorescens FW300-N1B4

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Reactions and Genes Minimal media pH9
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Lysine decarboxylase:
L-lysine + H+→cadaverine + CO2 (EC 4.1.1.18)
Pf1N1B4_1136 +0.5
Pf1N1B4_4600 -0.1
Putrescine aminotransferase:
cadaverine + 2-oxoglutarate→5-aminopentanal + L-glutamate (EC 2.6.1.82)
No genes
Aminobutyraldehyde dehydrogenase:
5-aminopentanal + NAD+ + H2O→5-aminopentanoate + NADH + 2 H+ (EC 1.2.1.19)
Pf1N1B4_3024 +0.1
Pf1N1B4_3029 -0.1
Pf1N1B4_4264 +0.3
5-aminovalerate transaminase:
5-aminopentanoate + 2-oxoglutarate→glutarate semialdehyde + L-glutamate (EC 2.6.1.48)
Pf1N1B4_1733 -2.1
Pf1N1B4_4910 +0.0
Glutarate-semialdehyde dehydrogenase:
glutarate semialdehyde + NADP+ + H2O→glutarate + NADPH + 2 H+ (EC 1.2.1.20)
Pf1N1B4_1734 -1.1
Pf1N1B4_4931 +0.6
Pf1N1B4_5616 -0.3
Succinate--hydroxymethylglutarate CoA-transferase:
glutarate + succinyl-CoA→glutaryl-CoA + succinate (EC 2.8.3.13)
Pf1N1B4_1815 +0.0

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information