MetaCyc Pathway: L-arginine degradation II (AST pathway) in Pseudomonas fluorescens FW300-N1B4

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Reactions and Genes Minimal media pH9
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Arginine N-succinyltransferase:
L-arginine + succinyl-CoA→N2-succinyl-L-arginine + coenzyme A + H+
(EC 2.3.1.109)
Pf1N1B4_3442 N.D.
Pf1N1B4_3443 -0.7
Pf1N1B4_4797 +0.2
Pf1N1B4_5856 +0.2
Pf1N1B4_5857 N.D.
N-succinylarginine dihydrolase:
N2-succinyl-L-arginine + 2 H+ + 2 H2O→N2-succinyl-L-ornithine + 2 ammonium + CO2
(EC 3.5.3.23)
Pf1N1B4_3445 -1.0
Succinylornithine transaminase:
N2-succinyl-L-ornithine + 2-oxoglutarate→N2-succinyl-L-glutamate 5-semialdehyde + L-glutamate
(EC 2.6.1.81)
Pf1N1B4_3440 +1.5
Succinylglutamate-semialdehyde dehydrogenase:
N2-succinyl-L-glutamate 5-semialdehyde + NAD+ + H2O→N2-succinylglutamate + NADH + 2 H+
(EC 1.2.1.71)
Pf1N1B4_3444 N.D.
Succinylglutamate desuccinylase:
N2-succinylglutamate + H2O→L-glutamate + succinate
(EC 3.5.1.96)
Pf1N1B4_3447 -0.1

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information