MetaCyc Pathway: superpathway of purines degradation in plants in Pseudomonas fluorescens SBW25-INTG

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Reactions and Genes NAG (C)
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Adenosine-phosphate deaminase:
AMP + H+ + H2O→IMP + ammonium (EC 3.5.4.17; 3.5.4.6)
No genes
5'-nucleotidase:
GMP + H2O→guanosine + phosphate (EC 3.1.3.5)
PFLU_RS01380 -2.4
PFLU_RS06415 -0.4
PFLU_RS08400 +0.0
PFLU_RS10890 +0.5
Guanosine deaminase:
guanosine + H+ + H2O→xanthosine + ammonium (EC 3.5.4.15)
No genes
IMP dehydrogenase:
IMP + NAD+ + H2O→XMP + NADH + H+ (EC 1.1.1.205)
PFLU_RS10605 -0.0
PFLU_RS24735 N.D.
5'-nucleotidase:
IMP + H2O→inosine + phosphate (EC 3.1.3.5; 3.1.3.99)
PFLU_RS01380 -2.4
PFLU_RS06415 -0.4
PFLU_RS08400 +0.0
PFLU_RS10890 +0.5
Purine nucleosidase:
guanosine + H2O→guanine + D-ribofuranose (EC 3.2.2.1)
PFLU_RS20350 +0.0
Guanine deaminase:
guanine + H+ + H2O→xanthine + ammonium (EC 3.5.4.3)
PFLU_RS03295 -0.1
PFLU_RS22515 +0.2
Inosine nucleosidase:
inosine + H2O→hypoxanthine + D-ribofuranose (EC 3.2.2.2)
PFLU_RS20350 +0.0
5'-nucleotidase:
XMP + H2O→xanthosine + phosphate (EC 3.1.3.5)
PFLU_RS06415 -0.4
PFLU_RS08400 +0.0
PFLU_RS10890 +0.5
Xanthine dehydrogenase:
hypoxanthine + NAD+ + H2O→xanthine + NADH + H+ (EC 1.17.1.4)
PFLU_RS22500 -0.1
PFLU_RS22505 -0.6
PFLU_RS26280 -0.0
PFLU_RS26285 +0.1
Purine nucleosidase:
xanthosine + H2O→xanthine + D-ribofuranose (EC 3.2.2.1)
PFLU_RS20350 +0.0
Xanthine dehydrogenase:
xanthine + NAD+ + H2O→urate + NADH + H+ (EC 1.17.1.4)
PFLU_RS22500 -0.1
PFLU_RS22505 -0.6
PFLU_RS26280 -0.0
PFLU_RS26285 +0.1
Urate oxidase:
urate + dioxygen + H2O→(S)-5-hydroxyisourate + hydrogen peroxide (EC 1.7.3.3)
PFLU_RS04925 +0.3
PFLU_RS06770 -0.3
PFLU_RS21385 -0.1
Hydroxyisourate hydrolase:
(S)-5-hydroxyisourate + H2O→(S)-2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline + H+ (EC 3.5.2.17)
PFLU_RS00975 -0.1
PFLU_RS21380 -0.6
(S)-2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline + H+→(S)-(+)-allantoin + CO2 (EC 4.1.1.97)
No genes
Allantoinase:
(S)-(+)-allantoin + H2O→allantoate + H+ (EC 3.5.2.5)
No genes
Allantoicase:
allantoate + H2O→(S)-ureidoglycolate + urea (EC 3.5.3.4)
PFLU_RS21395 -0.7
Ureidoglycolate lyase:
(S)-ureidoglycolate→glyoxylate + urea (EC 4.3.2.3)
PFLU_RS21400 -0.6

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information