MetaCyc Pathway: myo-, chiro- and scyllo-inositol degradation in Klebsiella michiganensis M5al

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Reactions and Genes m-Inositol (C)
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Inositol 2-dehydrogenase:
myo-inositol + NAD+→scyllo-inosose + NADH + H+ (EC 1.1.1.18)
BWI76_RS03095 -2.9
BWI76_RS07220 +0.2
BWI76_RS07225 -0.2
BWI76_RS10220 N.D.
BWI76_RS14045 -0.1
scyllo-inositol + NAD+→scyllo-inosose + NADH + H+ (EC 1.1.1.370)
No genes
1D-chiro-inositol + NAD+→1-keto-D-chiro-inositol + NADH + H+ (EC 1.1.1.369)
No genes
1-keto-D-chiro-inositol→scyllo-inosose (EC 5.3.99.11)
No genes
Myo-inosose-2 dehydratase:
scyllo-inosose→3D-(3,5/4)-trihydroxycyclohexane-1,2-dione + H2O (EC 4.2.1.44)
BWI76_RS03105 -2.0
BWI76_RS10210 N.D.
BWI76_RS14050 -0.4
3D-(3,5/4)-trihydroxycyclohexane-1,2-dione + H2O→5-deoxy-D-glucuronate + H+ (EC 3.7.1.22)
BWI76_RS03090 -1.9
5-deoxy-D-glucuronate→5-dehydro-2-deoxy-D-gluconate (EC 5.3.1.30)
BWI76_RS03075 -2.5
5-dehydro-2-deoxygluconokinase:
5-dehydro-2-deoxy-D-gluconate + ATP→5-dehydro-2-deoxy-D-gluconate 6-phosphate + ADP + H+ (EC 2.7.1.92)
BWI76_RS03075 -2.5
BWI76_RS03085 -2.0
5-dehydro-2-deoxyphosphogluconate aldolase:
5-dehydro-2-deoxy-D-gluconate 6-phosphate→glycerone phosphate + 3-oxopropanoate (EC 4.1.2.29)
BWI76_RS03085 -2.0
Malonate-semialdehyde dehydrogenase (acetylating):
3-oxopropanoate + coenzyme A + NAD+→acetyl-CoA + CO2 + NADH (EC 1.2.1.18)
BWI76_RS02840 -0.1
BWI76_RS03070 -1.4

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information