MetaCyc Pathway: L-tyrosine degradation I in Pseudomonas stutzeri RCH2

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Reactions and Genes Vanillin 2 mM
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Aspartate transaminase:
L-tyrosine + 2-oxoglutarate→3-(4-hydroxyphenyl)pyruvate + L-glutamate (EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
Psest_1268 +0.1
Psest_1295 -1.8
Psest_1570 -0.0
Psest_1710 -0.0
Psest_1985 -0.0
Psest_1990 -0.1
Psest_3297 +0.2
Psest_0779 -0.9
4-hydroxyphenylpyruvate dioxygenase:
3-(4-hydroxyphenyl)pyruvate + dioxygen→homogentisate + CO2 (EC 1.13.11.27)
Psest_3514 -0.0
Psest_4071 +0.0
Homogentisate 1,2-dioxygenase:
homogentisate + dioxygen→4-maleyl-acetoacetate + H+ (EC 1.13.11.5)
Psest_3513 +0.4
Maleylacetoacetate isomerase:
4-maleyl-acetoacetate→4-fumaryl-acetoacetate (EC 5.2.1.2)
Psest_3511 -0.6
Fumarylacetoacetase:
4-fumaryl-acetoacetate + H2O→acetoacetate + fumarate + H+ (EC 3.7.1.2)
Psest_3512 -1.1

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information