MetaCyc Pathway: 4-hydroxybenzoate biosynthesis III (plants) in Rhodopseudomonas palustris CGA009

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Reactions and Genes PM with p-Coumaric (C)
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4-coumarate--CoA ligase:
4-coumarate + ATP + coenzyme A→(E)-4-coumaroyl-CoA + AMP + diphosphate
(EC 6.2.1.12)
TX73_008785 -0.0
TX73_009190 +1.9
(E)-4-coumaroyl-CoA + H2O→3S-(4-hydroxyphenyl)-3-hydroxy-propanoyl-CoA (EC 4.1.2.61)
TX73_009185 +1.0
3-hydroxyacyl-CoA dehydrogenase:
3S-(4-hydroxyphenyl)-3-hydroxy-propanoyl-CoA + NAD+→3-(4-hydroxyphenyl)-3-oxo-propanoyl-CoA + NADH + H+
(EC 1.1.1.35)
TX73_004220 -0.0
TX73_008775 -2.4
TX73_011910 -0.1
TX73_018155 -0.1
TX73_019255 +1.4
Acetyl-CoA C-acyltransferase (in reverse):
3-(4-hydroxyphenyl)-3-oxo-propanoyl-CoA + coenzyme A→4-hydroxybenzoyl-CoA + acetyl-CoA
(EC 2.3.1.16)
TX73_002660 +0.2
TX73_002750 +0.1
TX73_004215 -0.2
TX73_008765 +0.6
TX73_011915 +0.2
TX73_017920 +0.0
TX73_017940 +0.1
TX73_019245 +0.0
TX73_022530 +0.1
4-hydroxybenzoyl-CoA thioesterase:
4-hydroxybenzoyl-CoA + H2O→4-hydroxybenzoate + coenzyme A + H+
(EC 3.1.2.23)
TX73_009195 +1.3

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information