MetaCyc Pathway: superpathway of fermentation (Chlamydomonas reinhardtii) in Klebsiella michiganensis M5al

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Reactions and Genes a-Cyclodextrin (C)
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Formate C-acetyltransferase (in reverse):
pyruvate + coenzyme A→acetyl-CoA + formate (EC 2.3.1.54)
BWI76_RS03570 +0.0
BWI76_RS03575 -0.0
BWI76_RS09070 +0.2
BWI76_RS09075 +0.0
BWI76_RS09730 +0.6
BWI76_RS09735 +0.0
BWI76_RS10655 +0.6
BWI76_RS10660 +0.1
BWI76_RS21375 +0.2
Pyruvate decarboxylase:
pyruvate + H+→acetaldehyde + CO2 (EC 4.1.1.1)
BWI76_RS20520 -0.0
Acetaldehyde dehydrogenase (acetylating) (in reverse):
acetyl-CoA + NADH + H+→acetaldehyde + coenzyme A + NAD+ (EC 1.2.1.10)
BWI76_RS02835 -0.0
BWI76_RS03590 -0.2
BWI76_RS16905 -0.0
BWI76_RS17250 -0.2
BWI76_RS20790 -0.0
Pyruvate synthase:
pyruvate + coenzyme A + 2 an oxidized ferredoxin [iron-sulfur] cluster→acetyl-CoA + CO2 + H+ + 2 a reduced ferredoxin [iron-sulfur] cluster (EC 1.2.7.1)
BWI76_RS12730 +0.0
BWI76_RS18805 +0.1
Alcohol dehydrogenase (in reverse):
acetaldehyde + NADH + H+→ethanol + NAD+ (EC 1.1.1.1)
BWI76_RS00645 +0.1
BWI76_RS02835 -0.0
BWI76_RS03140 -0.1
BWI76_RS03320 +0.0
BWI76_RS12395 +1.4
BWI76_RS13800 -0.2
BWI76_RS15240 -0.0
BWI76_RS17250 -0.2
BWI76_RS25510 +0.0
BWI76_RS27960 +0.0
D-lactate dehydrogenase (in reverse):
pyruvate + NADH + H+→(R)-lactate + NAD+ (EC 1.1.1.28)
BWI76_RS12790 -1.2
BWI76_RS19515 +0.2
Ferredoxin hydrogenase (in reverse):
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+→H2 + 2 an oxidized ferredoxin [iron-sulfur] cluster (EC 1.12.7.2)
BWI76_RS22310 +0.3
BWI76_RS22315 +0.0
BWI76_RS22320 +0.1
BWI76_RS22325 -0.1
BWI76_RS22330 -0.4
BWI76_RS22335 +0.0
Phosphate acetyltransferase:
acetyl-CoA + phosphate→acetyl phosphate + coenzyme A (EC 2.3.1.8)
BWI76_RS03560 -0.1
BWI76_RS20240 N.D.
BWI76_RS20805 -0.2
BWI76_RS23150 +0.1
Acetate kinase (in reverse):
acetyl phosphate + ADP→acetate + ATP (EC 2.7.2.1; 2.7.2.15)
BWI76_RS18090 -0.0
BWI76_RS20235 N.D.
BWI76_RS20815 +0.0
BWI76_RS20820 -0.0
BWI76_RS23200 -0.1

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information