MetaCyc Pathway: glycine degradation in Pseudomonas fluorescens FW300-N2E3

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Reactions and Genes Doxycycline hyclate 0.0006 mg/ml
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glycine + NAD+ + a tetrahydrofolate→ammonium + a 5,10-methylenetetrahydrofolate + CO2 + NADH (EC 1.4.1.27)
AO353_08735 +0.2
Glycine hydroxymethyltransferase (in reverse):
glycine + a 5,10-methylenetetrahydrofolate + H2O→L-serine + a tetrahydrofolate (EC 2.1.2.1)
AO353_07665 -0.4
AO353_10495 -0.8
AO353_10530 +0.2
AO353_14020 N.D.
AO353_14025 +0.3
AO353_29335 -0.1
L-serine ammonia-lyase:
L-serine→ammonium + pyruvate (EC 4.3.1.17)
AO353_03505 +0.6
AO353_07775 -0.1
AO353_15500 -1.3

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information