MetaCyc Pathway: polyhydroxybutanoate biosynthesis in Acidovorax sp. GW101-3H11

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Reactions and Genes L-Threonine (N)
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Acetyl-CoA C-acyltransferase:
2 acetyl-CoA→acetoacetyl-CoA + coenzyme A (EC 2.3.1.16; 2.3.1.9)
Ac3H11_178 +0.2
Ac3H11_1916 -0.2
Ac3H11_1932 -0.2
Ac3H11_2303 +0.1
Ac3H11_2522 +0.2
Ac3H11_2740 N.D.
Ac3H11_2769 -0.1
Ac3H11_2994 -1.9
Ac3H11_3407 -0.2
Ac3H11_3408 +0.2
Ac3H11_3920 -0.2
Acetoacetyl-CoA reductase (in reverse):
acetoacetyl-CoA + NADPH + H+→(3R)-3-hydroxybutanoyl-CoA + NADP+ (EC 1.1.1.36)
Ac3H11_2302 -1.1
(3R)-3-hydroxybutanoyl-CoA + poly-[(R)-3-hydroxybutanoate]→poly-[(R)-3-hydroxybutanoate] + coenzyme A (EC 2.3.1.304)
Ac3H11_2304 -1.5

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information